Kathy J. The presence of semen in vaginal fluid, as identified by an acid phosphatase spot test, does not influence vaginal proinflammatory cytokine concentrations. Objective : determine whether semen, as detected by acid phosphatase, influences vaginal cytokines or secretory leukocyte protease inhibitor concentrations. Methods : pregnant women had vaginal fluid collected for Gram stain, acid phosphatase detection by colorimetric assay, and interleukin 1-Beta, interleukin-6, interleukin-8, and secretory leukocyte protease inhibitor measurement by enzyme immunoassay. Results for women with and without acid phosphatase were compared by Mann-Whitney test. There were no significant differences in proinflammatory cytokine concentrations; however, secretory leukocyte protease inhibitor concentrations were significantly higher among women with acid phosphatase. Conclusions : proinflammatory cytokine measurement does not appear to be affected by the presence of semen, but secretory leukocyte protease inhibitor is significantly higher when semen is present. Detection of semen by acid phosphatase was associated with higher vaginal SLPI concentrations, however, the presence of semen did not appear to influence vaginal proinflammatory cytokine concentrations.


MeSH terms
Infectious Diseases in Obstetrics and Gynecology
Some people may wish to remove semen from the vagina after sex, either for hygienic reasons or to try to prevent pregnancy. However, once semen enters the cervix through the vaginal canal, there is no scientifically proven way to remove it. There are a few ways to clean the vagina and the areas around it safely. However, if someone wishes to avoid becoming pregnant, they should seek appropriate medical advice. In this article, we look at how to clean the vagina after sex and how effective this is in removing semen. We also discuss how to prevent pregnancy using birth control options. The vagina is a flexible canal that connects the vaginal opening to the cervix. People often confuse the vagina with the vulva, which is the external part of the female genitalia. The vagina is self-cleaning, and there is no need to clean it immediately after sex.
Home Remedies
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Q: I am married for 3 years but we are still not blessed with a child. Everything is normal with both of us. Ovulation study shows normal cycle. I have observed that after the intercourse, the moment my husband withdraws his penis, all the semen comes out of the vagina. We tried using a pillow beneath, which helped in keeping the semen inside for few minutes. But after 10 minutes the semen comes out of the vagina. Could this be the cause of infertility?